A patient with bilateral sciatic neuropathies.

position in a floor-level cupboard with a depressed level of consciousness after ingesting an overdose of amitriptyline and alcohol the night before. She was transferred to hospital and treated for tricyclic antidepressant overdose and was found to have rhabdomyolysis. Her creatine kinase peaked at 70 000 units/L. Within 24 hours after admission, the patient recovered her normal level of consciousness and complained of bilateral hip, groin and buttock pain exacerbated by movement. She also had weakness, paresthesias and numbness in both lower extremities, more pronounced on the right. Following initial consideration of other possible causes, Neurology was consulted. Her examination demonstrated normal cranial nerves and upper extremity function. The patient had pain with passive flexion of the hips. There was bilateral weakness of leg extension (2/5), hip abduction (3/5), knee flexion (3/5), ankle dorsiflexion (4-/5), plantar flexion (4-/5), foot inversion (4-/5), foot eversion (4-/5), toe dorsiflexion (4-/5), and toe plantar flexion (4-/5), with each slightly worse for the right leg. Deep tendon reflexes were absent at both ankles but present and symmetric elsewhere, including at the knees and adductor muscles. Plantar responses were flexor. Sensory exam revealed decreased pinprick sensation over the right foot and the lateral lower right leg, along with minimally decreased pin prick sensation over the left sole and medial aspect of the left foot. On day seven of admission, an enhanced Computed Tomography (CT) scan of the pelvis revealed moderately large areas of low attenuation in the gluteus muscles bilaterally, right greater than left (see Figure). The normal fat planes surrounding the sciatic nerve in the sciatic notch (figure, arrows) are obscured by low attenuation fluid or hematoma. The low attenuation is rounded and more prominent on the left than on the right. The low attenuation fluid or hematoma may reflect tracking from the gluteal muscle or direct nerve injury. The findings were consistent with areas of muscle injury, infarct or hematoma due to pressure necrosis and reflected the degree of pressure injury to the gluteal and buttock area. No compartment syndrome was felt to be present by either ICU specialists or surgical consultants. Surgical decompression was considered but not performed. An ultrasound of the lower extremities was negative for deep venous thrombosis. The patient was discharged 11 days after admission, using a wheelchair to mobilize. The patient returned for nerve conduction studies nine weeks after her initial presentation. At that time she was taking gabapentin and oxycodone for neuropathic pain over both distal legs. She required a cane to ambulate and wore a right ankle